张伟 博士
副教授
2000-2004年 山东大学生命科学学院 学士
2004-2010年 中国科学院神经科学研究所 博士
2010-2016年 加州大学旧金山分校/霍华德休斯医学院 博士后
2017年至今 hth官网app生命科学学院 助理教授、副教授
2017年至今 hth官网app生命联合中心/清华-IDG/麦戈文脑科学研究院 研究员
● 研究兴趣、领域：
大脑与体内器官的双向交流由复杂的神经和激素系统控制，对维持人体的生理和心理稳态起着至关重要的作用。体内感受不仅广泛参与本能行为的调控，还会影响高级认知行为，例如记忆、情绪和自我意识。我们实验室采用“受体的生物物理学--神经元的细胞生物学—神经环路的功能学—动物行为学”这一自下而上的模式，探讨体内感受的分子与神经环路机制, 并进行神经-器官双向通讯与生理调控的多维度研究。
● 代表性论文：
1. Chenxi Liu*, Ning Tian, Pei Chang,Wei Zhang*. Mating reconciles fitness and fecundity by switching diet preference in flies.Nature Communications.2024.
2. Jierui Qin, Tingting Yang, Kexin Li，Ting Liu,Wei Zhang*. Pharyngeal mechanosensory neurons control food swallow in Drosophila melanogaster.eLife,2024.
3. Jie Yu, Xuan Guo, Shen Zheng,Wei Zhang*. A dedicate sensorimotor circuit enables fine texture discrimination by active touch.Plos Genetics.2023
4. Chenxi Liu*,Wei Zhang*. Molecular basis of somatosensation in insects.Current Opinion in Neurobiology, 2022
5. Yinjun Jia*, Shuaishuai Li, Xuan Guo, Bo Lei, Junqiang Hu, Xiao-Hong Xu,Wei Zhang*, Selfee, self-supervised features extraction of animal behaviors.Elife, 2022
6. Liwei Zhang*#, Xuan Guo#,Wei Zhang*. Nutrients and pheromones promote insulin release to inhibit courtship drive.Science Advances. 2022
7. Tingting Yang, Zixuan Yuan, Chenxi Liu, Ting Liu,Wei Zhang*. A neural circuit integrates pharyngeal sensation to control feeding.Cell Reports. 2021.
8. Rui Luo, Yuxiang Zhang, Yinjun Jia, Yan Zhang, Zongyang Li, Jieqing Zhao, Ting Liu,Wei Zhang*. Molecular basis and homeostatic regulation of Zinc taste.Protein & Cell. 2021.
9. Philip Hehlert,Wei Zhang, Martin C Göpfert, Drosophila Mechanosensory Transduction,Trends in Neurosciences, Volume 44, Issue 4, 323 - 335
10. Pingping Wang, Yinjun Jia, Ting Liu, Yuh-Nung Jan*,Wei Zhang*. Visceral Mechano-sensing Neurons Control Drosophila Feeding by Using Piezo as a Sensor.Neuron. 2020.
11. Chenxi Liu, Bei Zhang, Liwei Zhang, Tingting Yang, Zhewei Zhang, Zihua Gao,Wei Zhang. A neural circuit encoding mating states tunes defensive behavior in Drosophila.Nature Communications. 2020.
12. Liwei Zhang#*, Jie Yu#, Xuan Guo, Jianhua Wei, Ting Liu,Wei Zhang*. Parallel mechanosensory pathways direct oviposition decision of Drosophila.Current Biology. 2020.
13. Yawen Li #, Yufei Hu#, Jiawei Wang, Xin Liu*,Wei Zhang*; Linfeng Sun*. Structural Insights into a Plant Mechanosensitive Ion Channel MSL1.Cell Reports. 2020.
14. Yufei Hu, Zhilin Wang, Ting Liu,Wei Zhang*. Piezo-like Gene Regulates Locomotion in Drosophila Larvae.Cell Reports. 2019.
● 联系方式：
Tel: +86-10-62790589
E-mail:weizhang0505@126.com
